Abstract: The catalytic deoxygenating experiment of oxygen-bearing coal mine methane (CMM) was carried out in a bench-scale fluidized bed reactor with the spherical Cu-based catalyst. The effects of the bed temperature, the particle size and the space velocity were investigated on the oxygen removal efficiency and CO₂ selectivity. The raising bed temperature could promote the O₂ conversion due to the high activity of the catalyst. The O₂ conversion could reach more than 95% when the temperature was above 450 ℃. The smaller particle size was beneficial to the CO₂ selectivity of the catalyst because of the decreasing inner diffusion resistance. The lower space velocity also could improve the O₂ removal efficiency when the bed temperature was below 450 ℃ although the improvement almost disappears above 450 ℃ due to the increasing catalytic combustion rate. Additionally, by adjusting the CH₄/Air ratio, the catalytic deoxygenation adaptability of the fluidized bed reactor and the catalyst was evaluated for the variable oxygen content in CMM. The results indicate that the process has a perfect oxygen removal performance with the O₂ concentration less than 0.2% and the CO₂ selectivity more than 98% for the O₂ content from 5% to 15% in the simulated CMM.