Abstract: Mn/Al-SBA-15 absorbent was synthesized by impregnation using Al-SBA-15 prepared by grafting method as support, manganese acetate as precursor of active component. The samples were characterized by means of XRD, N₂ adsorption-desorption, NH₃-TPD, Py-FTIR and XPS. The adsorbent was used for adsorption desulfurization of simulated gasoline. The optimum molar ratio of Al/Si was determined through combining characterization of samples and their desulfurization performance. The mechanism of adsorption desulfurization was proposed. The regeneration properties were also studied. The results showed that when the molar ratio of Al/Si was 1:45, the performance of adsorbent was the best. The thiophene was adsorbed through acid-base reaction. The introduction of Al improved the stability and the regeneration of the adsorbent.