Abstract: The ultra-low asphaltene content of Golmud residue (asphaltene content:0.32%) was used as the hydrogenation feedstock. The effect of reaction conditions on the composition properties, colloidal stability parameters (CSP) and coke performance of the hydrogenation reaction samples was investigated. The results show that with the increase in hydrogenation temperature and reaction time, the content of asphaltene and saturated fraction increases, the content of colloid and aromatic fraction as well as the colloid stability parameter decrease, and the coke yield increases continuously. Meanwhile, as the degree of condensation of asphaltenes increases, the aromatic carbon ratio f_A increases continuously, the metals and heteroatoms are continuously removed during hydrogenation, V is easier to remove than Ni, and S is easier to remove than N. On the catalyst surface is a carbon-based substance similar to the graphite with ordered structure formed, leading to the continuous reduction in pore structure parameters of the catalyst. When the reaction temperature and time are 420 ℃ and 5 h, respectively, the pore structure damage of the catalyst is the most serious, and a dominant distribution of micropore appears.