Abstract: Three-dimensional graphene (PGO) was synthesized by spay-drying method.Pt/PGO catalyst was prepared through the improved liquid phase reduction method.The samples were characterized by XRD, BET and TEM.The results indicated that PGO was a three-dimensional crumpled structure material with 4-6 μm in length and 2.0-3.0 μm in width and the Pt nanoparticles with 4.2 nm were highly dispersed on the surface of PGO.The electro-catalytic activity and stability of the catalysts towards methanol electro-oxidation were investigated using cyclic voltammetry and chronoamperometry.The as-prepared Pt/PGO catalyst exhibits higher electro-catalytic activity and good stability during methanol electro-oxidation in comparison to Pt/GO catalysts.The enhanced catalytic performance is attributed to the high specific surface area of the 3D formation and utilization efficiency of Pt during methanol electro-oxidation.